To compare the outcomes of conventional IVF and ICSI on sibling oocytes.Retrospective analysis.Performance of ICSI on part of the oocytes and IVF on the remaining portion during the same cycle (sibling oocytes).135 couples (141 cycles) with male subfertility or with idiopathic infertility.Globally, the fertilization rate was not different between the ICSI and IVF, however, in patients with severe teratospermia, it was higher after ICSI (56.2 vs. 44.2 %, p<0.05). The fertilization failure rate was higher in the IVF group than in the ICSI group, globally, (12.1 % vs 2.8 %, p = 0.005), as well in patients with severe teratospermia. In the latter group, a higher number of top quality embryos were obtained after ICSI than after IVF. Of 57 cycles with severe teratospermia, only ICSI-embryos were transferred in 24, while only IVF-embryos were transferred in 11, resulting respectively in 8 and 3 clinical pregnancies.This study underscores that ICSI is useful in patients with teratospermia. Nevertheless, considering the chances of obtaining a successful fertilization after IVF and lower risk of chromosomal aberrations, we recommend performing both IVF and ICSI on sibling oocytes during the first treatment cycle in patients with teratospermia.

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Bénédicte, Becker Evelyne, Bertrand Jeannine, Van Hoeck Godelieve, Verhaegen Serge, Rozenberg Annick, Delvigne,.Outcome of conventional IVF and ICSI on sibling oocytes in patients suffering from teratospermia.. 51 (4),163-9.

Bénédicte, Becker Evelyne, Bertrand Jeannine, Van Hoeck Godelieve, Verhaegen Serge, Rozenberg Annick, Delvigne,"Outcome of conventional IVF and ICSI on sibling oocytes in patients suffering from teratospermia." 51

Bénédicte, Becker Evelyne, Bertrand Jeannine, Van Hoeck Godelieve, Verhaegen Serge, Rozenberg Annick, Delvigne,"Outcome of conventional IVF and ICSI on sibling oocytes in patients suffering from teratospermia."