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Journal of the American Pharmaceutical Association | Vol.44, Issue.6 | | Pages 338-340

The influence of the rate of an intermittent administration upon the lethal dose of digitalis tincture in pigeons

Daniel P. N. Tsao

Abstract

A study of the rate of administration of digitalis tincture in pigeons by a five-minute-interval injection over a wide range indicated that there is a relation between the lethal dose and rate of administration at the levels of from 0.0126 to 0.1661 ml./ Kg./5 min. during the experimental time of from thirty to three hundred and sixty minutes. The lethal dose increases with the increase of the rate of administration but within the experimental time employed this linear increase was not considered to be significant.

Original Text (This is the original text for your reference.)

The influence of the rate of an intermittent administration upon the lethal dose of digitalis tincture in pigeons

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Keywords

administration rate dose increase tincture relation ml Kg5 min pigeons

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Daniel P. N. Tsao,.The influence of the rate of an intermittent administration upon the lethal dose of digitalis tincture in pigeons. 44 (6),338-340.

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