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Computational and Mathematical Methods in Medicine | Vol.2013, Issue. | | Pages

Computational and Mathematical Methods in Medicine

Modelling Tumour Oxygenation, Reoxygenation and Implications on Treatment Outcome

Iuliana Toma-Dasu,Alexandru Dasu  
Abstract

Oxygenation is an important component of the tumour microenvironment, having a significant impact on the progression and management of cancer. Theoretical determination of tissue oxygenation through simulations of the oxygen transport process is a powerful tool to characterise the spatial distribution of oxygen on the microscopic scale and its dynamics and to study its impact on the response to radiation. Accurate modelling of tumour oxygenation must take into account important aspects that are specific to tumours, making the quantitative characterisation of oxygenation rather difficult. This paper aims to discuss the important aspects of modelling tumour oxygenation, reoxygenation, and implications for treatment.

Original Text (This is the original text for your reference.)

Modelling Tumour Oxygenation, Reoxygenation and Implications on Treatment Outcome

Oxygenation is an important component of the tumour microenvironment, having a significant impact on the progression and management of cancer. Theoretical determination of tissue oxygenation through simulations of the oxygen transport process is a powerful tool to characterise the spatial distribution of oxygen on the microscopic scale and its dynamics and to study its impact on the response to radiation. Accurate modelling of tumour oxygenation must take into account important aspects that are specific to tumours, making the quantitative characterisation of oxygenation rather difficult. This paper aims to discuss the important aspects of modelling tumour oxygenation, reoxygenation, and implications for treatment.

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Iuliana Toma-Dasu,Alexandru Dasu,.Modelling Tumour Oxygenation, Reoxygenation and Implications on Treatment Outcome. 2013 (),.

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