In this work, the distribution of different lengths ROH (runs of homozygosity) in six cattle breeds was described. A total of 122 animals from six cattle breeds (Holstein, Simmental, Austrian Pinzgau, Ayrshire, MRI-Meuse Rhine Issel and Slovak Pinzgau) were analysed. The ROH approach was used to distinguish Slovak Pinzgau population from other investigated breeds as well as to differentiate between ancient and recent inbreeding. The average number of ROH per animal ranged from 17.06 in Holstein to 159.22 in Ayrshire. The highest number of short ROH (ancient inbreeding) was found in Simmental, followed by Ayrshire. The Ayrshire and MRI had a higher proportion of longer ROH distributed across the whole genome, revealing recent inbreeding. ROH were identified and used to estimate molecular inbreeding coefficients (FROH). The highest level of inbreeding from the investigated breeds was found out in Ayrshire with the same tendency for all length categories compared to Slovak Pinzgau with higher ancient inbreeding. Ancient inbreeding was only observed in Holstein population. A similar trend is becoming apparent even for Slovak Pinzgau, showing the second smallest recent inbreeding. Therefore, it is necessary to preserve the given population in the original phenotype and prevent further increase of inbreeding especially in endangered breeds.

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runs homozygosity roh approach molecular inbreeding coefficients

,.GENOMIC VARIABILITY AMONG CATTLE POPULATIONS BASED ON RUNS OF HOMOZYGOSITY. 21 (1 sup),.

,"GENOMIC VARIABILITY AMONG CATTLE POPULATIONS BASED ON RUNS OF HOMOZYGOSITY" 21

,"GENOMIC VARIABILITY AMONG CATTLE POPULATIONS BASED ON RUNS OF HOMOZYGOSITY"