MHC class I proteins mediate functions in anti-pathogen defense. MHC diversity has already been investigated by many studies in model avian species, but here we chose the bar-headed goose, a worldwide migrant bird, as a non-model avian species. Sequences from exons encoding the peptide-binding region (PBR) of MHC class I molecules were isolated from liver genomic DNA, to investigate variation in these genes. These are the first MHC class I partial sequences of the bar-headed goose to be reported. A preliminary analysis suggests the presence of at least four MHC class I genes, which share great similarity with those of the goose and duck. A phylogenetic analysis of bar-headed goose, goose and duck MHC class I sequences using the NJ method supports the idea that they all cluster within the anseriforms clade.

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barheaded goose goose antipathogen defense mhc diversity liver genomic dna peptidebinding region nj method genes mhc class i molecules partial

Lei Wei,Qinglong Liang,Xinwei Wang,Hongxuan He,.MHC class I loci of the Bar-Headed goose (Anser indicus). 33 (3),.

Lei Wei,Qinglong Liang,Xinwei Wang,Hongxuan He,"MHC class I loci of the Bar-Headed goose (Anser indicus)" 33

Lei Wei,Qinglong Liang,Xinwei Wang,Hongxuan He,"MHC class I loci of the Bar-Headed goose (Anser indicus)"