The objective of this study was to assess the utility of endobronchial ultrasound (EBUS) morphology of lymph nodes in predicting benign cytology of transbronchial needle aspirates in a prospective observational study. Five ultrasonic morphological characteristics of mediastinal and hilar lymph nodes were recorded: size, shape, margins, echogenic appearance and the presence of a central blood vessel. These characteristics were correlated with the final diagnosis. A total of 402 consecutive patients (237 males and 165 females) undergoing EBUS were studied. The final diagnosis was malignant disease in 244 (60.6%) and benign disease in 153 (38.05%) subjects. Out of 740 sampled nodes, in 463 (62.6%) malignant cells were identified, whereas in 270 (36.5%) nodes, no malignant cells were identified. On univariate analysis small size, triangular shape and the presence of a central vessel were predictive of a benign aetiology. In the final multivariate model, a predictive probability of 0.811 (95% CI 0.72–0.91) for benign disease was found if lymph node size was

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ultrasonic morphological characteristics benign disease size triangular shape mediastinal and benign cytology of transbronchial needle margins echogenic appearance blood endobronchial ultrasound ebus morphology of lymph nodes

Pratibha Gogia,Tabassum Z. Insaf,William McNulty,Afroditi Boutou,Andrew G. Nicholson,Zaid Zoumot,Pallav L. Shah,.Endobronchial ultrasound: morphological predictors of benign disease. 2 (1),.

Pratibha Gogia,Tabassum Z. Insaf,William McNulty,Afroditi Boutou,Andrew G. Nicholson,Zaid Zoumot,Pallav L. Shah,"Endobronchial ultrasound: morphological predictors of benign disease" 2

Pratibha Gogia,Tabassum Z. Insaf,William McNulty,Afroditi Boutou,Andrew G. Nicholson,Zaid Zoumot,Pallav L. Shah,"Endobronchial ultrasound: morphological predictors of benign disease"