To evaluate the association between maternal serum DDT/DDE levels and risk of hypospadias.A case-control study in Mexico City was conducted during 1997-1999 among 41 subjects with hypospadias and 28 controls. Blood samples were obtained from study subjects. Information was obtained using a standardized questionnaire. Data were analyzed using multivariate logistic regression models.Maternal DDT and DDE levels showed no association with hypospadias (OR 1.13; 95% CI 0.24-5.29 and OR = 0.48; 95% CI 0.15-1.60, respectively). Associated factors were older age of mothers (OR 8.69; 95% CI 1.69-44.9), and working during pregnancy (OR 4.68; 95% CI 1.15-18.9).Information about the endocrine effects of different levels of DDT/DDE in human subjects is scarce; dosage may be a determinant factor of the type of effect. The English version of this paper is available at:http://www.insp.mx/salud/index.html.

+More

hypospadias logistic regression ddtdde dde of hypospadiasa

Silvia, Flores-Luévano Paulina, Farías Mauricio, Hernández Patricia, Romano-Riquer Jean Philippe, Weber Eric, Dewailly Juan, Cuevas-Alpuche Isabelle, Romieu,.[DDT/DDE concentrations and risk of hypospadias. Pilot case-control study].. 45 (6),431-8.

Silvia, Flores-Luévano Paulina, Farías Mauricio, Hernández Patricia, Romano-Riquer Jean Philippe, Weber Eric, Dewailly Juan, Cuevas-Alpuche Isabelle, Romieu,"[DDT/DDE concentrations and risk of hypospadias. Pilot case-control study]." 45

Silvia, Flores-Luévano Paulina, Farías Mauricio, Hernández Patricia, Romano-Riquer Jean Philippe, Weber Eric, Dewailly Juan, Cuevas-Alpuche Isabelle, Romieu,"[DDT/DDE concentrations and risk of hypospadias. Pilot case-control study]."