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Italian journal of neurological sciences | Vol.16, Issue.1-2 | | Pages 83-89

Italian journal of neurological sciences

Reflex epilepsy of the fowl and its transfer to normal chickens by brain embryonic grafts.

M A, Teillet N, Guy N, Fadlallah G, Le Gal La Salle B, Schuler C, Batini N, Le Douarin R, Naquet  
Abstract

The genetic photosensitive epilepsy of the Fayoumi chicken was transferred to normal chickens by in situ grafts at 2 days of incubation, of both the prosencephalic and mesencephalic brain vesicles taken from epileptic embryos. However, mesencephalic graft is sufficient to allow convulsions under sound stimulation. Typical EEG patterns are recorded in chimeras having the prosencephalon plus or not the mesencephalon. We conclude that, in this mutant, the whole neural tissue is affected, but the seizure generator is localized inside the mesencephalon, and specific sensory pathways are necessary for seizures to occur.

Original Text (This is the original text for your reference.)

Reflex epilepsy of the fowl and its transfer to normal chickens by brain embryonic grafts.

The genetic photosensitive epilepsy of the Fayoumi chicken was transferred to normal chickens by in situ grafts at 2 days of incubation, of both the prosencephalic and mesencephalic brain vesicles taken from epileptic embryos. However, mesencephalic graft is sufficient to allow convulsions under sound stimulation. Typical EEG patterns are recorded in chimeras having the prosencephalon plus or not the mesencephalon. We conclude that, in this mutant, the whole neural tissue is affected, but the seizure generator is localized inside the mesencephalon, and specific sensory pathways are necessary for seizures to occur.

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M A, Teillet N, Guy N, Fadlallah G, Le Gal La Salle B, Schuler C, Batini N, Le Douarin R, Naquet,.Reflex epilepsy of the fowl and its transfer to normal chickens by brain embryonic grafts.. 16 (1-2),83-89.

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