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Human Vaccines & Immunotherapeutics | Vol., Issue. | 2020-09-29 | Pages

Neutralizing antibody response elicited by SARS-CoV-2 receptor-binding domain

Jan, Jia-Tsrong Tao, Mi-Hua Chou, Yu-Chi Hu, Che-Ming Jack Huang, Ping-Han Chen, Hui-Wen Lin, Yi-Ling Tsai, Hsiao-Han Liao, Bo-Hung

Abstract

A safe and effective vaccine candidate is urgently needed for the ongoing COVID-19 pandemic, caused by SARS-CoV-2. Here we report that recombinant SARS-CoV-2 RBD protein immunization in mice is able to elicit a strong antibody response and potent neutralizing capability as measured using live or pseudotyped SARS-CoV-2 neutralization assays.

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Neutralizing antibody response elicited by SARS-CoV-2 receptor-binding domain

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Keywords

sarscov2 neutralization assays sarscov2 rbd protein

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Jan, Jia-Tsrong, Tao, Mi-Hua, Chou, Yu-Chi, Hu, Che-Ming Jack,Huang, Ping-Han, Chen, Hui-Wen, Lin, Yi-Ling, Tsai, Hsiao-Han, Liao, Bo-Hung,.Neutralizing antibody response elicited by SARS-CoV-2 receptor-binding domain. (),.

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