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A multishot lensless camera in development could aid disease diagnosis

A multishot lensless camera in development could aid disease diagnosis

A multishot lensless camera in development could aid disease diagnosis
Schematic of the layout for a lensless camera. Credit: Keating/Liu Labs, Penn State

A new type of imaging that does not require a lens and uses reconfigurable particle-based masks to take multiple shots of an object is being developed by researchers at Penn State. The electric-field directed self-assembling mask technology is expected to have uses in lower-cost and faster disease diagnosis, the enhancement of optical microscopy, and may even lead to thinner cellphone technology.

How it works

The researchers create a mask of microscopic gold wires and place it near the object that will be imaged. The mask scatters the light reflected off the object and an collects the light. An rearranges the particles in the mask, producing a new mask with every iteration, and the system records each new image. The multiple light captures are then computationally reconstructed into the original object image, resulting in highly improved resolution and quality.

"We are not the only group to do lens-free imaging," explained Jennifer Miller, a doctoral candidate in chemistry and a first author on a paper recently published online in ACS Nano. "What is different about our work is that typically you would need to make multiple masks and physically move them around to get multiple images. This becomes bulky and expensive and negates some of the simplicity that is the advantage of lens-free imaging."

In typical microscopy, there exists a trade-off between the field of view and the power of the resolution, so a 10x field is wider than a100x field. By using a lens-free imaging technology, it is possible to combine a wide field of view with high magnification for lower-cost and faster diagnosis of disease. This could be especially useful in developing countries where high-end microscopes are not available.

"Traditional masks are passive," said co-first author Cheng-Yu Wang, in electrical engineering. "We can add functionalization to our microwire, like polarization, selectivity and plasmonic effects, that make our imaging system more powerful."

In the case of cellphones, one major contributor to their bulk is due to the needing to be a certain distance to the detector. A lens-free camera could help minimize the space requirement. Likewise, a lens-free system added to a cellphone could turn the cellphone into a low-power microscope.

Along with Miller and Yang, senior authors on the ACS Nano paper, "Particle-based reconfigurable scattering for lensless imaging," are Christine Keating, distinguished professor of chemistry, and Zhiwen Liu, professor of electrical engineering.


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More information: Jennifer R. Miller et al. Particle-Based Reconfigurable Scattering Masks for Lensless Imaging, ACS Nano (2020). DOI: 10.1021/acsnano.0c04490
Journal information: ACS Nano
Citation: A multishot lensless camera in development could aid disease diagnosis (2020, September 23) retrieved 23 September 2020 from https://phys.org/news/2020-09-multishot-lensless-camera-aid-disease.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Original Text (This is the original text for your reference.)

A multishot lensless camera in development could aid disease diagnosis

A multishot lensless camera in development could aid disease diagnosis
Schematic of the layout for a lensless camera. Credit: Keating/Liu Labs, Penn State

A new type of imaging that does not require a lens and uses reconfigurable particle-based masks to take multiple shots of an object is being developed by researchers at Penn State. The electric-field directed self-assembling mask technology is expected to have uses in lower-cost and faster disease diagnosis, the enhancement of optical microscopy, and may even lead to thinner cellphone technology.

How it works

The researchers create a mask of microscopic gold wires and place it near the object that will be imaged. The mask scatters the light reflected off the object and an collects the light. An rearranges the particles in the mask, producing a new mask with every iteration, and the system records each new image. The multiple light captures are then computationally reconstructed into the original object image, resulting in highly improved resolution and quality.

"We are not the only group to do lens-free imaging," explained Jennifer Miller, a doctoral candidate in chemistry and a first author on a paper recently published online in ACS Nano. "What is different about our work is that typically you would need to make multiple masks and physically move them around to get multiple images. This becomes bulky and expensive and negates some of the simplicity that is the advantage of lens-free imaging."

In typical microscopy, there exists a trade-off between the field of view and the power of the resolution, so a 10x field is wider than a100x field. By using a lens-free imaging technology, it is possible to combine a wide field of view with high magnification for lower-cost and faster diagnosis of disease. This could be especially useful in developing countries where high-end microscopes are not available.

"Traditional masks are passive," said co-first author Cheng-Yu Wang, in electrical engineering. "We can add functionalization to our microwire, like polarization, selectivity and plasmonic effects, that make our imaging system more powerful."

In the case of cellphones, one major contributor to their bulk is due to the needing to be a certain distance to the detector. A lens-free camera could help minimize the space requirement. Likewise, a lens-free system added to a cellphone could turn the cellphone into a low-power microscope.

Along with Miller and Yang, senior authors on the ACS Nano paper, "Particle-based reconfigurable scattering for lensless imaging," are Christine Keating, distinguished professor of chemistry, and Zhiwen Liu, professor of electrical engineering.


Explore further

Researchers develop flat lens a thousand times thinner than a human hair

More information: Jennifer R. Miller et al. Particle-Based Reconfigurable Scattering Masks for Lensless Imaging, ACS Nano (2020). DOI: 10.1021/acsnano.0c04490
Journal information: ACS Nano
Citation: A multishot lensless camera in development could aid disease diagnosis (2020, September 23) retrieved 23 September 2020 from https://phys.org/news/2020-09-multishot-lensless-camera-aid-disease.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
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